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To foster an ecosystem for HK-SZ collaboration in biotech, the   employment opportunities and drive the growth of upstream and
            two governments need to devise a long-term, concrete and    downstream industries, as well as generating a good source of
            comprehensive development plan. In this chapter, we shall focus   tax revenues.
            on some of the issues hampering HK-SZ collaboration and
            propose policy recommendations for the reference of the two   Nonetheless, there is a lack of world-class leading biotech
            governments. To ensure long-term collaborative development   corporation or industrial cluster in either Hong Kong or Shenzhen.
            under “one zone, two parks” at the Loop, coordination on the   Despite the rapid growth of industry in Shenzhen, there are
            policy-making level should be stepped up to prevent talent and   relatively fewer leading core enterprises and major multinationals.
            enterprises from flowing one way and congregating into a    SMEs make up the majority of biomedical companies in
            particular park owing to differences in tax and rental incentives.   Shenzhen, along with a few medium-sized companies that
                                                                        constitute the backbone of the industry. Thus, there are few
                                                                        companies with the potential to grow into leading enterprises.
            | Establishing anchor institutions in                       One of the reasons behind so is the absence of anchor institutions,
              the region to expedite development                        which exert significant influence on their surrounding areas.
              of a biotech industrial cluster                           However, there is no lack of successful cases of anchor institutions
                                                                        in other areas. Take Zhangjiang Hi-Tech Park in Shanghai as an
            Anchor institutions usually refer to core institutions or enterprises   example. Right from the start of development, the municipal
            in a specific area. There are two types of anchor institutions, one   government and the operator of the Park took the initiative to
            of which is top universities or mega research institutes. Through   attract giant multinational pharmaceutical corporations, such as
            fundamental scientific research and knowledge transfer, these   Roche and GSK, to set up regional headquarters or R&D centres
            institutions support local enterprises of various scales with basic   in the park. The establishment fostered the formation of a local
            research and help nurture spin-off enterprises of high potential   biomedical supply chain, hence attracting and nurturing
            into unicorns, thereby generating huge profits with research   local innovative pharmaceutical companies like Green Valley,
            outcomes. The other type of anchor institutions is large    CITIC Guojian Pharmaceutical Industry Co., MicroPort and
            enterprises, such as large pharmaceutical corporations, which   Fudan-Zhangjiang. Another good example can be found in Greater
            draw small and medium-sized enterprises (SMEs) to relocate near   Boston in the US, which houses an all-rounded and multifaceted
            them so as to take part in the upstream or downstream       world-class biotech industrial cluster. In the following section, we
            operations or seek opportunities for acquisition by the giants.   shall analyse the example of Kendall Square in Greater Boston
            Anchor institutions play a crucial role in the development of the   before proposing a multipronged strategy to build a biotech
            local economy and industries as they create numerous        industrial cluster in the Loop by establishing anchor institutions.


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