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                 Kendall Square: Greater Boston’s Biotech                   In 2004, MIT and Harvard University jointly established the Broad
       Policy recommendations for the governments of Hong Kong and Shenzhen
                 Industrial Cluster                                         Institute, a biotech mega research institute with the objective of
                                                                            enhancing in-depth, cross-disciplinary, cross-institutional and
                 Encompassing Boston and Cambridge, Massachusetts, Greater   multinational research to find solutions for complex, contemporary
                 Boston is a top cluster for health sciences in the US, where 19 out   biomedical conundrums. The Institute’s advanced research further
                 of the 20 largest pharmaceutical companies locate their offices.   fosters industrial, academic and research collaboration; promotes
                 With Kendall Square as its centre and strategic proximity to the   the commercialisation of research outcomes; and nurtures the
                 Massachusetts Institute of Technology (MIT) and Harvard    rapid development of a biotech industrial cluster in Kendall Square.
                 University, the area is frequently named “the most innovative
                 square mile on the planet” (see Figure 12). Attracted by top   Kendall Square sets a good example for the development of a
                 universities, a top-notch talent pool and policy incentives, large   biotech industrial cluster in the Loop. By drawing in star and
                 pharmaceutical corporates (marked in pink in the figure), including   leading enterprises within a short period of time, the Loop can
                 Novartis, Pfizer, AstraZeneca, etc., have set up their regional   quickly create a favourable environment for local start-ups and
                 headquarters or R&D centres in the area. Many start-ups with   industrial development. At the same time, nurturing local potential
                 great potentials (marked in orange in the figure) can also be found   start-ups into unicorns will advance the overall industrial growth in
                 there. Among them, many are spin-off companies of universities,   the area. Building a biotech mega research institute is, in the long
                 such as Moderna, a spin-off of Harvard University that developed   run, beneficial to industrial, academic and research collaboration
                 a COVID-19 vaccine. These start-ups have gradually grown into   building upon strong basic research and to encourage the
                 unicorns. They also stand a good chance of going public or being   industrialisation of advanced technology in the area.
                 acquired by conventional large pharmaceutical enterprises.



















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